Smoking cigarettes and reading the news is very natural, two incompatible concepts. But Natural News readers are human beings after all, and thus not quite perfect. Moreover, even the most sophisticated raw foodist are probably aware, or even one who sometimes likes to puff. For them, research on the substance that appeared to reverse the health effects of smoking may have a ring of good news. Inositol, the connection is found in many foods, it seems to stop the threat of lung cancer from cigarettes dead in their tracks.
Inositol is a natural nutrient found in various forms, the most common of which is myo-inositol. Inositol is part of vitamin B complex group, although this is not officially recognized as one of the vitamins and the RDA has not been installed. As vitamins are soluble in water, and, consequently, not very well stored in the body. You must constantly be replaced in the diet, although about 4 grams per day is produced from glucose in the kidneys.
Inositol found in various foods such as nuts, seeds, oats, rice, beans, corn, Nut, liver, pork, veal, whole grains, cantaloupe, most citrus fruit, lecithin granules, as well as embryos of wheat. It is available as a supplement in capsule or powdered form. Jarrow Formulas makes a dry form that is easily available from online retailer of health. There are others. Inositol powder is a delicious sweet, creamy taste and is a fantastic addition to smoothies.
Two prominent researchers have found inositol prevents cancer
Dr. Lee Wattenberg, known as the father of Chemoprevention, searched for several decades starting in 1970, `S to find natural compounds that theoretically could prevent cancer and applied research on the methodology of his discoveries. After testing several molecules, he found inositol to have great potential. Using various research models he was able to prove that inositol can prevent lung cancer. It has been reported that malnutrition has increased the chances of cancer occurs, but Dr. Wattenberg was among the first to show that the total nutrient can actually prevent cancer, indeed the possibility of opening.
A few years after Dr. Wattenberg, Dr Abdul Kalam Shamsuddin, known as the father of IP6 (inositol hexaphosphate), also showed that inositol was able to prevent cancer, demonstrating the preventive value in conjunction with colon cancer. Research by Dr. Shamsuddin, that inositol affects health in several ways, mainly because it is in all cells of the human body, and is one of the main components of cell membranes or linings where it facilitates communication between different organelles and molecules in a process known as cell signaling.
Why Don `T cigarette companies out of the hands with a bottle of inositol each carton of cigarettes?
Some bright young singer of one of the largest tobacco companies, may have been an idea to increase sales by telling everyone that inositol, an inexpensive supplement to prevent lung cancer. But for the cigarette companies to buy the idea would be a recognition that cigarettes cause cancer. Such recognition would create a huge legal liability for any company to manufacture and sell cigarettes.
Inositol provides many other benefits in the body
Inositol is an essential nutrient for the growth of hair. This helps prevent the hardening of arteries and plays an important role in the formation of lecithin and the metabolism of fats and cholesterol. This helps remove fat from the liver. Inositol has a calming effect on the brain, and is successfully used at high doses in the treatment of mental disorders such as depression, bipolar, obsessive-compulsive and panic. Inositol is also used for insomnia, retinopathy, and nervous bulimia and binge eat. This is useful for diabetic neuropathy, brain cramps, as well as to normalize cholesterol and triglyceride levels.
Symptoms of deficiency are atherosclerosis, constipation, hair loss, high blood cholesterol, irritability, mood fluctuations, and skin eruptions. Consumption of large quantities of caffeine, usually leads to inositol deficiency. As the consumption of coffee is often accompanied by cigarette smoking, the lack of inositol may have been a decisive factor in smoking-induced lung cancer, so prevalent at a time when smoking was in style.
Research continues to improve knowledge about the mechanisms by which inositol Works
As a natural compound, there is little incentive for pharmaceutical companies to research inositol. Natural compounds are not patentable. However, some researchers continue to examine the effects of inositol in an attempt to identify the specific mechanisms by which it prevents lung cancer in cigarette smokers. Here is a summary of the abstracts from the latest research. It is truly amazing, or perhaps a better word about the offender that smoking public was not aware of these results, which date from the time Dr. steadily. Watterberg and Shamsuddin.
The results of the study
In phosphatidyl-inositol-3-kinase-AKT path of becoming an important regulator of survival of tumor cells. Substances that hinder this way have great potential in treating cancer. In Biochemical Pharmacology, December 2008, the researchers report, myo-inositol related potentiating cell death. This effect correlated with down regulation of various gene products, which are intermediary cell survival, proliferation, metastasis and invasion, all known to be regulated by NF-kappaB. In the complex inositol blocked NF-kappaB activation induced by cigarette smoke.
Cancer Epidemiology Biomarkers and Prevention, August 2006, reported in clinical studies conducted to assess the safety of admissibility, the maximum tolerated dose, and the potential chemopreventive effects of myo-inositol in smokers with bronchial abnormal development of cells. Smokers between the ages of 40 and 74 attended the escalation of doses in the range of 12 to 30 grams a day of myo-inositol for one month to determine the maximum tolerated dose, which was 18 grams a day. Ten new subjects were enrolled to take the maximum tolerated dose for 3 months. Side effects in the present, were mild and mainly gastrointestinal nature. The significant reduction in the rate of abnormal cells are observed (91% compared to 48% in the control group). A significant reduction in systolic and diastolic blood pressure by an average of 10 mm Hg was observed after administration of 18 grams of inositol per day for a month or more.
Researchers reported that smoking is a major risk factor for cardiovascular disease. Nicotine has been shown to alter gene expression. In a study reported in the physiological Genomics, April, 2001, the researchers are trying to identify the various ways through which changes in gene expression was held. They found expression of more than 4000 genes in the human coronary artery endothelial cells and identified a number of nicotine-modulated genes coding for proteins involved in signal transduction or transcriptional regulation. Among those genes that regulate inositol phospholipids way.
Journal of Experimental Lung Research in December 2000, the mice undergoing whole-body exposure for 6 hours a day, 5 days a week for 5 months in a mixture of cigarette sidestream smoke and principal, and then uses another 4 months in a controlled air environment to beat for lung tumors. In 7 independent experiments, the number of lung cancer has increased in each experiment, as well as increased incidence of lung tumors in 5 experiments. Several compounds were evaluated by their capacity for such tumors, but none of them reduce the incidence or multiplicity of lung tumors. Nevertheless, a mixture of dietary myo-inositol and dexamethasone (a synthetic steroid hormone that acts as an antiinflammatory and immune system suppressant) was effective in reducing the incidence and multiplicity of lung tumors as compared with control. That effect was also seen when the animals fed with myo-inolitol-dexamethasone mixture once they were removed from the smoke. The researchers concluded that people who recently quit may benefit from this complex.
Scientists have recognized that the chronic effects in mice and rats to cigarette smoke affects T-cell response, which may be due to reduced T-cell proliferation and T-dependent antibody responses in humans and animals exposed to cigarette smoke. In a study reported in the Journal of Pharmacology and Experimental Therapy, April, 2000, the researchers tried to find a mechanism, in which tobacco smoke affects T cell function. They found that spleen cells from animals with chronic exposure to nicotine have depleted inositol stores and reduced ability to increase intracellular calcium. Their results indicate that smoking is a chronic T cell energy and the reduction of activity in violation of ways and inositol layer is stored as a result, decreased the amount of inositol-sensitive calcium.
Mice were fed a diet supplement myo-inositol, and exposed for 5 months in a mixture of sidestream and mainstream cigarette smoke, a study reported in the carcinogenesis, July, 1999. In animals fed the control diet alone, the average number of overt lung tumors 2.1. In the animal is given to the control diet plus inositol mixture, the number of overt lung tumors 1.0. Researchers concluded that the mixture is an effective prevention measure against the regime of initiation of tobacco-induced lung tumors.
In a study reported in the journal Immunology, April, 1996, as T and B lymphocytes in animals treated with chronic nicotine exhibited decreased ability to mobilize intracellular calcium and the inability to complete the cell cycle. Nicotine cells significantly lost their ability to manage inositol synthesis. This reaction continues for at least 2 weeks after nicotine treatment was discontinued. Researchers concluded that in vivo chronic nicotine exposure leads to T-cells, loss of energy and activity, and can lead to nicotine / cigarette smoke caused by the suppression of the immune system.
Friday, 21 August 2009
Tuesday, 6 January 2009
L&M - Just what the doctor ordered!
Cigarette smoking has become a style icon for many people around the world. The cigarette has become very common among people of every age, ra
ce and social class. You can find people smoking cigarette in many places you visit. Whether you attend a social function or family, you will most likely find people smoking cigarette. Even people don’t mind to smoke in the parks and in the public places. You will find people smoking in the offices, parties and get together. There are different brands of cigarette which you can find in the market. There are few companies, which offer the best quality of cigarettes on the market.
L&M is one of the popular cigarettes created by the company Ligget&
Myers. Ligget & Myers Tobacco Company was founded in 1873 after a partnership between J.E. Ligget and George Smith Meyers was established. The trade name of the cigarette was derived from the initials of its producer L&M “Ligget & Meyers”. The cigarettes by L&M Company are most preferred by a large amount of people. L&M Company offers the best quality of cigarettes to the people with a smooth and rich tasting flavor. The L&M Company makes sure that they are able to maintain the quality and rich taste in the cigarette while still maintaining a competitive price. 
Nowadays, this famous brand is produced by Altria Group Inc. It is especially blend of the best sorts of tobacco - Virginia, Oriental and Burley ones. At present, L&M cigarettes are welcome in several varieties and each of them has its own peculiarity.
The flavor of the L&M cigarettes is very high and rich in taste and flavor. That is why L&M cigarettes are liked by many people around the world. L&M cigarettes have six brands or flavors to choose from that will fit any person’s desire. They are the L&M Filter/Classic Box cigarettes, L&M Lights Box cigarettes, L&M One Box cigarettes, L&M Super Lights Box cigarettes, L&M Menthol Lights Box and L&M Menthol Box cigarettes. They also have their Slims flavors such as the L&M Slims Tune/NEO cigarettes, L&M Slims Vibe and the L&M Slims Mixx. They are sold in packs of 10 cigarettes and 20 cigarettes. The L&M Classic or Filter in the red box is strong in taste and is for those who desire a bolder flavor. The L&M Lights and Super Lights are specially made for those who like soft tasting cigarettes that are also smoother, while the L&M One is designed for a regular smoker, who is looking for a simple yet flavor cigarette to enjoy daily. The L&M Menthol/Menthol Lights will be most appreciated for its fresh tobacco taste, but also for it less bold flavor. L&M make’s many styles and flavors that are perfect for its wide range of customers.
L&M cigarettes are sold worldwide in about 60 countries all over the world. Millions of smokers around the world love its strong and aromatic taste. Even if it is sold at a low price, it can still guarantee to give smokers their utmost pleasure and delight. L&M cigarettes are not only tasty but easy on your pocket book.
ce and social class. You can find people smoking cigarette in many places you visit. Whether you attend a social function or family, you will most likely find people smoking cigarette. Even people don’t mind to smoke in the parks and in the public places. You will find people smoking in the offices, parties and get together. There are different brands of cigarette which you can find in the market. There are few companies, which offer the best quality of cigarettes on the market.L&M is one of the popular cigarettes created by the company Ligget&
Myers. Ligget & Myers Tobacco Company was founded in 1873 after a partnership between J.E. Ligget and George Smith Meyers was established. The trade name of the cigarette was derived from the initials of its producer L&M “Ligget & Meyers”. The cigarettes by L&M Company are most preferred by a large amount of people. L&M Company offers the best quality of cigarettes to the people with a smooth and rich tasting flavor. The L&M Company makes sure that they are able to maintain the quality and rich taste in the cigarette while still maintaining a competitive price. 
Nowadays, this famous brand is produced by Altria Group Inc. It is especially blend of the best sorts of tobacco - Virginia, Oriental and Burley ones. At present, L&M cigarettes are welcome in several varieties and each of them has its own peculiarity.
The flavor of the L&M cigarettes is very high and rich in taste and flavor. That is why L&M cigarettes are liked by many people around the world. L&M cigarettes have six brands or flavors to choose from that will fit any person’s desire. They are the L&M Filter/Classic Box cigarettes, L&M Lights Box cigarettes, L&M One Box cigarettes, L&M Super Lights Box cigarettes, L&M Menthol Lights Box and L&M Menthol Box cigarettes. They also have their Slims flavors such as the L&M Slims Tune/NEO cigarettes, L&M Slims Vibe and the L&M Slims Mixx. They are sold in packs of 10 cigarettes and 20 cigarettes. The L&M Classic or Filter in the red box is strong in taste and is for those who desire a bolder flavor. The L&M Lights and Super Lights are specially made for those who like soft tasting cigarettes that are also smoother, while the L&M One is designed for a regular smoker, who is looking for a simple yet flavor cigarette to enjoy daily. The L&M Menthol/Menthol Lights will be most appreciated for its fresh tobacco taste, but also for it less bold flavor. L&M make’s many styles and flavors that are perfect for its wide range of customers.
L&M cigarettes are sold worldwide in about 60 countries all over the world. Millions of smokers around the world love its strong and aromatic taste. Even if it is sold at a low price, it can still guarantee to give smokers their utmost pleasure and delight. L&M cigarettes are not only tasty but easy on your pocket book.
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